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(4) neither intervention (comparison standard; n28 patients). Methadone dose increases were double blind. Vouchers had monetary value and were exchangeable for goods and services.

Patients were getting the drug. 8220;Use of LAAM has been less than hoped for since its approval by the Food and Drug Administration,8221; says Rolley E. Johnson, Pharm. D, associate professor of psychiatry, who headed the Hopkins study. Early studies didn8217;t test participants8217; responses at various dosages, and under the cautious little-by-little approach to giving the medication, it appeared less effective than methadone at the first stage of treatment.

Under King Goujian, Yue recovered from its early reverses and fully annexed the lands of its rival in 473 BC, the Yue kings then moved their capital center from their original home around Mount Kuaiji in present-day Shaoxing to the former Wu capital at present-day Suzhou. With no southern power to turn against Yue, Chu opposed it directly and, in 333 BC, yues former lands were annexed by the Qin Empire in 222 BC and organized into a commandery named for Kuaiji in Zhejiang but initially headquartered in Wu in Jiangsu.]