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Some examples of their physiological roles include, The visual sense, GPCRs are also involved in immune-modulation and directly involved in suppression of TLR-induced immune responses from T cells. Involved in growth and metastasis of some types of tumors, GPCRs are integral membrane proteins that possess seven membrane-spanning domains or transmembrane helices. The extracellular parts of the receptor can be glycosylated and these extracellular loops also contain two highly conserved cysteine residues that form disulfide bonds to stabilize the receptor structure. Rat ‚ Rats are various medium-sized, long-tailed rodents of the superfamily Muroidea.

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