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Detailed information

In 2015, it was the eighth-largest drug company in the based on sales revenue. AstraZeneca has a portfolio of products for major areas including cancer, cardiovascular, gastrointestinal, infection, neuroscience, respiratory. The company was founded in 1999 through the merger of the Swedish Astra AB and it has made numerous corporate acquisitions, including Cambridge Antibody Technology, MedImmune, Spirogen and Definiens.

The FDA has resisted offering such a guarantee, according to people with knowledge of the matter. A possible compromise would have the agency give drug makers projected review timelines about two and a half months after they file their applications, including an indication of when label negotiations would begin, among other benchmarks. These would not be firm guarantees, however. Also at issue in the talks is FDA oversight of advertising and promotion. Members of PhRMA, the trade group, are voluntarily submitting commercials to the FDA, but want the agency to examine the ads quickly so the companies can craft campaigns and buy airtime efficiently.

Genetic modification of domesticated silkworms is used to facilitate the production of more types of silk. Silk fabric was first developed in ancient China, the earliest example of silk fabric is from 3630 BC, and it was used as wrapping for the body of a child from a Yangshao culture site in Qingtaicun at Xingyang, Henan. Legend gives credit for developing silk to a Chinese empress, Leizu, because of its texture and lustre, silk rapidly became a popular luxury fabric in the many areas accessible to Chinese merchants. Silk was in demand, and became a staple of pre-industrial international trade.]