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Vivax or P. ovale malarial parasites, artemether can also be used in treating and preventing trematode infections of schistosomiasis when used in combination with praziquantel. Artemether is rated category C by the FDA based on animal studies where artemisinin derivatives have shown an association with fetal loss, some studies, however, do not show evidence of harm. Possible side effects include cardiac effects such as bradycardia and QT interval prolongation, also, possible central nervous system toxicity has been shown in animal studies. Plasma artemether level was found to be lower when the product was used with lopinavirritonavir.

Since usually the vast majority of investigators depend on 945; 0. 05, this means that a research finding is more likely true than false if (1 8722; 946;) R gt; 0.]