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Transformation in bacteria was first demonstrated in 1928 by British bacteriologist Frederick Griffith, Griffith discovered that a strain of Streptococcus pneumoniae could be made virulent after being exposed to heat-killed virulent strains. Griffith hypothesized that some transforming principle from the strain was responsible for making the harmless strain virulent. In 1944 this transforming principle was identified as being genetic by Oswald Avery, Colin MacLeod and they isolated DNA from a virulent strain of S. pneumoniae and using just this DNA were able to make a harmless strain virulent. They called this uptake and incorporation of DNA by bacteria transformation, the results of Avery et al.

Rookie Brock Nelson got on the board first with his first NHL goal at the 2:26 mark.]